The Henry M. Jackson Foundation for the Advancement of Military Medicine

Advancing Military Medicine

Search Results - leukemia

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Small Molecule Therapeutics for Acute Myeloid Leukemia and Solid Tumors (HJF 490-17)
A technology related to novel methods of using small molecule compounds for treating myeloid neoplasms and solid tumor is available for licensing or collaboratively developing from HJF. Applications and Advantages Novel therapeutic targets for treating AML Targeted therapy for cancer patients with overexpression or activating mutation of SETBP1 Innovation...
Published: 3/20/2026   |   Updated: 2/24/2025   |   Inventor(s): Yang (Dennis) Du, Nhu Nguyen
Keywords(s): Acute Myeloid Leukemia, AML, Cancer, Leukemia, Oncogene, SETBP1, Small Molecule, Therapeutics
Category(s): Therapeutic
Small Molecule Inhibitors of ERG Oncoprotein - (HJF 578-20, HJF 393-15, and HJF 324-13)
HJF scientists have developed a first-in-class family of novel and potent small molecule ERG inhibitors that can be used as targeted therapeutics for malignant diseases with overexpression of ERG oncoproteins. Therapeutic indications may include prostate cancer, leukemia, and colorectal cancer. Applications and Advantages First-in-class small molecule...
Published: 3/19/2026   |   Updated: 2/2/2023   |   Inventor(s): Albert Dobi, Sanjay Malhotra, Mallesh Pandrala, Binil Eldhose
Keywords(s): Cancer, Colorectal Cancer, ERG, Leukemia, Oncogene, Prostate Cancer, Small Molecule, Therapeutics
Category(s): Therapeutic